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Experimental Study on Brucella abortus Strain RB51 Vaccinated Water Buffalo (Bubalus bubalis) Challenged with Virulent...
ISSN: 1927 - 520X
Publisher: author
Experimental Study on Brucella abortus Strain RB51 Vaccinated Water Buffalo (Bubalus bubalis) Challenged with Virulent...
Indexed in
Agriculture and Food Sciences
ARTICLE-FACTOR
1.3
Article Basics Score: 3
Article Transparency Score: 2
Article Operation Score: 3
Article Articles Score: 2
Article Accessibility Score: 3
SUBMIT PAPER ASK QUESTION
International Category Code (ICC):
ICC-0202
Publisher: Lifescience Global Inc.
International Journal Address (IAA):
IAA.ZONE/192710566520X
eISSN
:
1927 - 520X
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ISSN Validator
Abstract
The study was conducted to determine the efficacy of Brucella abortus strain RB51 (RB51) vaccine in preventing abortion in pregnant water buffalo (Bubalus bubalis) experimentally challenged using the intravenous route, with a local pathogenic strain of B. abortus biovar 1 (Trinidad 1). Thirty-two female water buffalo calves aged 6-10 months were randomly divided into three groups for the vaccination trial using the subcutaneous route: Group I animals received recommended dose (RD) vaccine twice 4 weeks apart, Group II was vaccinated twice 18 weeks apart and Group III (control) received saline once. At approximately 6 months of pregnancy following natural breeding, the animals were challenged by the intravenous route with 2.5 x 108 to 4.4 x 108 colony forming units of a local strain of B. abortus, Trinidad 1. Blood samples were collected, pre-challenge and post-challenge, for serological assay using the BPAT and the animals were monito...
