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PHARMACOKINETICS OF CEFQUINOME ON SINGLE INTRAVENOUS ADMINISTRATION IN OSMANABADI GOATS
ISSN: 2277 - 7601
Publisher: author
PHARMACOKINETICS OF CEFQUINOME ON SINGLE INTRAVENOUS ADMINISTRATION IN OSMANABADI GOATS
Indexed in
Agriculture and Food Sciences
ARTICLE-FACTOR
1.3
Article Basics Score: 3
Article Transparency Score: 2
Article Operation Score: 3
Article Articles Score: 3
Article Accessibility Score: 3
SUBMIT PAPER ASK QUESTION
International Category Code (ICC):
ICC-0202
Publisher: Kiran Abasaheb More
International Journal Address (IAA):
IAA.ZONE/2277390887601
eISSN
:
2277 - 7601
VALID
ISSN Validator
Abstract
Experiment was performed on six healthy Osmanabadi goats of either sex having age above 9 months and weighing around 30 to 35 kg to study the different pharmacokinetic parameters after single intravenous administration @ 2 mg/kg body weight by microbiological assay technique. After intravenous administration of the drug, blood samples (4 ml each) of Osmanabadi goats were collected from external jugular vein using disposable needles in clot activator tubes at different time intervals. The schedule of blood collection for pharmacokinetic studies after intravenous administration was at 0, 5, 10, 15, 30 min and 1, 2, 4, 6, 8, 10, 12 and 24 hrs. The serum levels of cefquinome were estimated by microbiological assay technique using large glass plate. Different Pharmacokinetic parameters were calculated as described by different scientists. The peak serum concentration, distribution half life, elimination half life, volume of distribution, t...
