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Synthesis and biological activity of 2-((3-Cyano-4,6-distyrylpyridin-2-yl) thio) acetamide and its cyclized form
ISSN: 2716 - 9375
Publisher: author
Synthesis and biological activity of 2-((3-Cyano-4,6-distyrylpyridin-2-yl) thio) acetamide and its cyclized form
Indexed in
Biology and Life Sciences
ARTICLE-FACTOR
1.3
Article Basics Score: 3
Article Transparency Score: 3
Article Operation Score: 2
Article Articles Score: 2
Article Accessibility Score: 3
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International Category Code (ICC):
ICC-0402
Publisher: Algerian Journal Of Biosciences
International Journal Address (IAA):
IAA.ZONE/2716118779375
eISSN
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2716 - 9375
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Abstract
In this paper, 2-((3-Cyano-4,6-distyrylpyridin-2-yl)thio)acetamide (2) and its cyclized form, 3-amino-4,6-distyrylthieno[2,3-b]pyridine-2-carboxamide (3), were prepared and their structure characterizations were performed by the means of elemental and spectroscopic analyses. Their biological activity as insecticides against cowpea aphid Aphis craccivora Koch using acetamiprid insecticide as a reference was studied. The bioassay results for compounds (2) and (3) against nymphs of cowpea aphid showed that the LC50 values were 0.192 and 0.841 ppm, respectively, after 24 h of treatment but the LC50 values were 0.041 and 0.095 ppm, respectively, after 48 h of treatment. Furthermore, the bioassay results for compounds (2) and (3) showed that the LC50 values were 1.233 and 2.949 ppm, respectively, after 24 h of treatment and the LC50 values were 0.142 and 0.270 ppm, respectively, after 48 h of treatment against adults of cowpea aphid. Given ...
