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Unripe Fruit's Extract of Quince (Cydonia oblonga Miller) as a Potent Alpha-amylase Inhibitor
ISSN: 0976 - 7614Publisher: author   
Unripe Fruit's Extract of Quince (Cydonia oblonga Miller) as a Potent Alpha-amylase Inhibitor
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Biology and Life Sciences
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1.3
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International Category Code (ICC):
ICC-0402
Publisher: Journal Of Advanced Laboratory Research In Biology Society..
International Journal Address (IAA):
IAA.ZONE/097653007614
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0976 - 7614
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Abstract
The use of alpha-amylase inhibitors has recently gained in popularity with the success and growth of carbohydrate restricted diets. In this study, two different stages from the unripe fruits of quince (Cydonia oblonga Miller) have been tested for their potentiality in alpha-amylase inhibition as a key enzyme in carbohydrates assimilation. Our results revealed that addition of different concentrations from extracts (0, 2, 4, 6, 8mg) of dry mass of each stage of unripe fruits resulted in drastically decrease in the enzymatic activity of alpha-amylase by the percent of (0%, 42.6%, 21%, 26.3%, and 16.9%) for the stage 1. Extracts from the stage 2 were more effective in enzymatic inhibition (0%, 26.9%, 3.8%, 0.2%, and 0.4%). The GC/MS analysis revealed that quince extract contains (sorbitol, quinic acid, p-vinylphenol and cyclopropane carboxylic acid). To explore which components are involved in the inhibition process, two pure components ...