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Role of lipoic acid (Thioctic acid) in improving vitality of different tissue culture cells
ISSN: 2090 - 3308
Publisher: author
Role of lipoic acid (Thioctic acid) in improving vitality of different tissue culture cells
Indexed in
Biology and Life Sciences
ARTICLE-FACTOR
1.3
Article Basics Score: 3
Article Transparency Score: 3
Article Operation Score: 3
Article Articles Score: 3
Article Accessibility Score: 2
SUBMIT PAPER ASK QUESTION
International Category Code (ICC):
ICC-0402
Publisher: Journal Of Applied Veterinary Sciences Rabie Fayed
International Journal Address (IAA):
IAA.ZONE/209054423308
eISSN
:
2090 - 3308
VALID
ISSN Validator
Abstract
The present obtained experimental results proved that addition of lipoic acid (LA) with its sodium salt in ratio of 0.1ml mole (mM) in the growth media has improved their physiological activities of different cell lines including MDBK, VERO and BHK21. Such cells remained normal for relative longer time comparing with the cell culture provided with media without lipoic acid (LA). The improvement of used cell lines was ascribed to the addition of lipoic acid (LA) dihydrolipoic acid, (DHLA) as protein free media supplement. As Lipoic acid (LA) and its dihydrolipoic acid (DHLA) are involved in several aspects of cell energy and amino acid metabolism, as well as in defense against oxidative stress and apoptosis; both components initiated the production of glutathione which antagonizes the oxidative effect of free radicals on cells that harmfully affects cell metabolism .This study is in need to involve more investigation covering other use...
