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Sulfonyl thiosemicarbazones: synthesis, characterization and antibacterial activity
ISSN: 2582 - 8789
Publisher: author
Sulfonyl thiosemicarbazones: synthesis, characterization and antibacterial activity
Indexed in
Biology and Life Sciences
ARTICLE-FACTOR
1.3
Article Basics Score: 3
Article Transparency Score: 2
Article Operation Score: 3
Article Articles Score: 2
Article Accessibility Score: 2
SUBMIT PAPER ASK QUESTION
International Category Code (ICC):
ICC-0402
Publisher: The Applied Biology & Chemistry Journal
International Journal Address (IAA):
IAA.ZONE/258295438789
eISSN
:
2582 - 8789
VALID
ISSN Validator
Abstract
The reaction of sulfonyl ketones (1-3) with thiosemicarbazide under reflux conditions yielded the sulfonyl thiosemicarbazones (4-6) in good to potential amounts (72-80%). The structure of new compounds (4-6) was confirmed by different spectral (IR, 1H NMR, 13C NMR, MS) and analytical techniques. The investigation of antibacterial screening data revealed that all the tested compounds (4-6) exhibited moderate to decent antibacterial activity against S. pyogenes, S. aureus and E. coli strains. The compounds 4-6 depicted zones of inhibition, i.e., 20.3 mm, 21.2 mm and 19.6 mm against S. pyogenes strain, respectively.
