×
Suggest this Article to:
TOP INDEXERS
Public Article
-
verified
Effect of Herbal Syrup Linkus on Acute and GrossToxicity and Electrolytes in Blood and Organs
ISSN: 2617 - 9482
Publisher: author
Effect of Herbal Syrup Linkus on Acute and GrossToxicity and Electrolytes in Blood and Organs
Indexed in
Health Sciences
ARTICLE-FACTOR
1.3
Article Basics Score: 2
Article Transparency Score: 3
Article Operation Score: 3
Article Articles Score: 2
Article Accessibility Score: 2
SUBMIT PAPER ASK QUESTION
International Category Code (ICC):
ICC-0702
Publisher: Bahria University Medical And Dental College
International Journal Address (IAA):
IAA.ZONE/2617100199482
eISSN
:
2617 - 9482
VALID
ISSN Validator
Abstract
Objective: To evaluate the effect of herbal syrup Linkus on acute and gross toxicity and electrolytes level in blood and organs.Materials and Methods: This interventional study was carried out in the department of Pharmacology, Faculty ofPharmacy,University of Karachi after approval from BASR-KU. In this study twenty-eight healthy rabbits of either sex weighing0.90 kg to 1.2 kg.All animals were equally divided into four groups, one served as control group while, remaining three groupsreceived herbal syrup Linkus at three different doses. Acute toxicity was tested in mice by Lorke’s method whereas effect ongross toxicity, blood and organ electrolytes was evaluated in Rabbits.Results: Herbal syrup Linkus exhibited LD50 values greater than 5 gm / kg per 24 hrs. No gross toxicity and mortality wasobserved during the whole experimental period. Non significant changes were observed in blood and organ electrolytes (Calcium,Potassium and Sodi...
