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Evaluation of Retinoblastoma According to HistologicalGrading, TNM Staging and Age at Presentation
ISSN: 2617 - 9482Publisher: author   
Evaluation of Retinoblastoma According to HistologicalGrading, TNM Staging and Age at Presentation
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Health Sciences
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1.3
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International Category Code (ICC):
ICC-0702
Publisher: Bahria University Medical And Dental College
International Journal Address (IAA):
IAA.ZONE/2617100759482
eISSN
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2617 - 9482
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Abstract
ABSTRACTObjective: To evaluate retinoblastoma, according to histological grades, TNM staging and age at presentation.Materials and Methods: This cross sectional study was conducted in Department of Pathology BMSI- JPMC Karachi from1st January 2009 to 31st December 2013 during whicha total of 80 cases of retinoblastoma were received. Out of which 68 werereviewed and morphological diagnosis was done on H&E staining. Histological grades and TNM staging were categorized.The data was analyzed by using SPSS version 22.Results: In 80 cases of retinoblastoma the mean age of patients was 3.64 years with 3-4 years (53.75%) of age being thecommonest. Amongst 68 cases, well differentiated retinoblastoma were seen in 7.35%, moderately differentiated 11.76%, poorlydifferentiated 26.47% and undifferentiated 51.41% cases. Varied pattern of TNM staging were observed. Majority (60.29%)in stage IV followed by 19.11% in stage I and 10.29% each in TNM sta...