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Comparison of Neutrophil Gelatinase Associated Lipocalinwith Serum Creatinine for Early Detection of Decrease inEstima...
ISSN: 2617 - 9482
Publisher: author
Comparison of Neutrophil Gelatinase Associated Lipocalinwith Serum Creatinine for Early Detection of Decrease inEstima...
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Health Sciences
ARTICLE-FACTOR
1.3
Article Basics Score: 2
Article Transparency Score: 2
Article Operation Score: 2
Article Articles Score: 2
Article Accessibility Score: 3
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International Category Code (ICC):
ICC-0702
Publisher: Bahria University Medical And Dental College
International Journal Address (IAA):
IAA.ZONE/2617100879482
eISSN
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2617 - 9482
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Abstract
Objective: To determine the accuracy of Neutrophil Gelatinase Associated Lipocalin (NGAL) at 2 h compared to serumcreatinine at 48 h after Computerized Tomography (CT) scan with contrast medium for early detection of decrease in estimatedGlomerular Filtration Rate (eGFR).Materials and Methods:This Cross Sectional Study was carried out in Departments of Chemical Pathology and RadiologyPNS SHIFA Karachi from 1stFebruary 2014 to 31st Jan 2015. One hundred and ten patients undergoing CT scan with contrastwereincluded. Serum creatinine wasmeasured byJaffé assay using Alkaline Picrate reagent on Modular P800 (Roche) analyzer beforeand 48 h after CT scan. eGFR was calculated by Modification of Diet in Renal Disease (MDRD) formula. Patients were dividedinto AKI and non-AKI groups. NGAL was analyzed by NGAL Reagent Kit on Triage meter pro at 2 h after contrast.Results: Out of 110 patients, 5 (4.54%) developed Acute Kidney Injury (AKI) 2 h afte...
