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Association and Interaction Effect between VEGF Receptor-2 (VEGFR-2) Gene Polymorphisms and Dietary Pattern on Blood L...
ISSN: 1929 - 5634Publisher: author   
Association and Interaction Effect between VEGF Receptor-2 (VEGFR-2) Gene Polymorphisms and Dietary Pattern on Blood L...
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Health Sciences
ARTICLE-FACTOR
1.3
Article Basics Score: 2
Article Transparency Score: 3
Article Operation Score: 3
Article Articles Score: 3
Article Accessibility Score: 3
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International Category Code (ICC):
ICC-0702
Publisher: Lifescience Global Inc.
International Journal Address (IAA):
IAA.ZONE/1929106685634
eISSN
:
1929 - 5634
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Abstract
Background: Vascular endothelial growth factor receptor-2 (VEGFR-2) and diet are related to blood lipid health. Gene-diet interaction studies can identify the risks. The objectives are to determine associations, and interaction effects between VEGFR-2 gene polymorphisms (rs1870377 and rs2071559) and dietary patterns on blood lipids in multiethnic Malaysian adults. Methods: Dietary intakes of 509 (153 Malay, 179 Chinese, and 177 Indian) Malaysians were obtained from food frequency questionnaire for the construction of dietary patterns using factor analysis. Anthropometric measurements: body mass index and blood pressure; and biomarkers: glycated hemoglobin, total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and total cholesterol/HDL-C ratio were determined. Genotyping of rs1870377 and rs2071559 was performed by real-time PCR using Taqman probes. Results...