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The Gut Microbiota and Epigenetics
ISSN: 1929 - 5634
Publisher: author
The Gut Microbiota and Epigenetics
Indexed in
Health Sciences
ARTICLE-FACTOR
1.3
Article Basics Score: 2
Article Transparency Score: 2
Article Operation Score: 2
Article Articles Score: 2
Article Accessibility Score: 2
SUBMIT PAPER ASK QUESTION
International Category Code (ICC):
ICC-0702
Publisher: Lifescience Global Inc.
International Journal Address (IAA):
IAA.ZONE/1929106995634
eISSN
:
1929 - 5634
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Abstract
The human gut microbiota presents a strong influence on health and disease development. Metagenomic analysis has revealed the importance of the interaction between the genomes of food, gut microbiota and the host. Also, the establishment of humanized mouse gut microbiota in appropriate animal models has further contributed to the understanding of its function. The composition of the gut microbiota presents a significant impact on the risk of disease development supported by findings of substantial individual variations. Many low molecular weight bacterial substances have been indicated to affect chromatin remodeling, regulation of apoptosis, cellular differentiation and inflammation. The gut microbiota has also been linked to the etiology of cancer because of how it can alter dietary exposures. Furthermore, microbial metabolites have been associated with epigenetic modifications, reversible heritable changes in gene expression without...
