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Nutritional Status of Pregnant Mothers Influence the Health in Adult Life of their Children
ISSN: 1929 - 5634
Publisher: author
Nutritional Status of Pregnant Mothers Influence the Health in Adult Life of their Children
Indexed in
Health Sciences
ARTICLE-FACTOR
1.3
Article Basics Score: 3
Article Transparency Score: 3
Article Operation Score: 2
Article Articles Score: 3
Article Accessibility Score: 3
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International Category Code (ICC):
ICC-0702
Publisher: Lifescience Global Inc.
International Journal Address (IAA):
IAA.ZONE/1929107665634
eISSN
:
1929 - 5634
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Abstract
Pregnancy and fetal development are periods of rapid growth and cell differentiation when mother and offspring are vulnerable to changes. Adverse events during development can be linked to an increased risk in developing metabolic diseases. Growth restriction in utero is associated with the development of obesity, hypertension, and diabetes. In these processes, the liver plays a fundamental role. The aim of this work was to evaluate the effects of a low protein diet in pregnant and lactating mothers on the antioxidant status of the offspring liver. To reproduce real conditions, we used an experimental rat model. Both ROS and the protective antioxidant systems have to work in coordination to reach a state of redox homeostasis. Excess generation of ROS may result in cell death or different pathological processes. The study also highlights the complex nature of malnutrition injury in which ROS correlates with the hepatic injury in a caus...
