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Expression of BRAF V600E in Tissue Samples of Colorectal Carcinoma and ItsCorrelation with Various Clinico-Pathologica...
ISSN: 2617 - 9482
Publisher: author
Expression of BRAF V600E in Tissue Samples of Colorectal Carcinoma and ItsCorrelation with Various Clinico-Pathologica...
Indexed in
Health Sciences
ARTICLE-FACTOR
1.3
Article Basics Score: 2
Article Transparency Score: 2
Article Operation Score: 2
Article Articles Score: 3
Article Accessibility Score: 3
SUBMIT PAPER ASK QUESTION
International Category Code (ICC):
ICC-0702
Publisher: Bahria University Medical And Dental College
International Journal Address (IAA):
IAA.ZONE/261797049482
eISSN
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2617 - 9482
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Abstract
Objective: To determine the expression of BRAF V600E in tissue samples of colorectal carcinoma and to correlate it withvarious clinico-pathological parameters.Study design and setting: Cross-sectional study was conducted at department of Pathology, Pakistan Navy Station Shifahospital Karachi from 1st March 2016 to 28th February 2019Methodology: Total of 51 cases of colorectal cancer were analyzed for immunohistochemical staining using BRAFantibodies on representative tissue blocks. Clinical and pathological records were retrieved for data collection. The resultsof immunohistochemical analysis were correlated with the recorded clinico-pathological parameters.Results: In this study 51 cases of colorectal cancer were analyzed for immune expression of BRAF V600E. The age ofthe patients ranged from 14 to 85 years with the mean age of 60.96 years. Among the 51 cases, 37(72.5%) cases were malesand 14(27.4%) were females. 37(72.5%) were local...
