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Expression And Scoring Of HER2/Neu in Variants of Prostate Adenocarcinoma
ISSN: 2617 - 9482Publisher: author   
Expression And Scoring Of HER2/Neu in Variants of Prostate Adenocarcinoma
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Health Sciences
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1.3
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International Category Code (ICC):
ICC-0702
Publisher: Bahria University Medical And Dental College
International Journal Address (IAA):
IAA.ZONE/261797319482
eISSN
:
2617 - 9482
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Abstract
Objective: To evaluate the immunohistochemical expression and scoring of HER2/neu in different variants of adenocarcinomaof prostate and to compared the association of HER2/neu expression with biological behavior and risk factors of prostateadenocarcinoma.Study Design and Setting: Cross sectional study in which all clinically suspected prostate adenocarcinoma cases receivedat the laboratory Saddar Karachi during the years 2015 and 2016 were evaluated for morphological features of adenocarcinoma.Methodology: This cross sectional study was carried out using prostate biopsies of clinically suspected prostateadenocarcinoma. The diagnosis of adenocarcinoma was confirmed and histological characterization was done by evaluatingthe morphological features. The tumors were graded according to the revised 2015 Gleason’s grouping. Immunohistochemicalanalysis for HER2/neu expression was performed in the most representative tumor block. SPSS versio...