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Low Dose Theophylline and Tiotropium Rotacap as Add on Therapy in COPDPatients-Clinical Trial
ISSN: 2617 - 9482
Publisher: author
Low Dose Theophylline and Tiotropium Rotacap as Add on Therapy in COPDPatients-Clinical Trial
Indexed in
Health Sciences
ARTICLE-FACTOR
1.3
Article Basics Score: 3
Article Transparency Score: 3
Article Operation Score: 3
Article Articles Score: 3
Article Accessibility Score: 3
SUBMIT PAPER ASK QUESTION
International Category Code (ICC):
ICC-0702
Publisher: Bahria University Medical And Dental College
International Journal Address (IAA):
IAA.ZONE/261797759482
eISSN
:
2617 - 9482
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Abstract
Objectives: To compare the role of low dose Theophylline and Tiotropium rotacap in improving the lung functions andday to day life of patients suffering from COPD.Study Design and Setting: A Clinical trial study was conducted at Department of Pharmacology and Therapeutics, BMSIin association with Department of Chest Medicine, JPMC.Methodology: This study was planned as an open label and parallel clinical trial study. A total of 168 patients of COPDwere selected for this study and only 161 patients completed the 3 months duration of the study. The enrolled patients weregrouped into 2, namely A and B. Tab. Theophylline 350 mg was given to Group A in two divided doses while Tiotropiumrotacap18μg through rotahaler was given to group B once a day.Results: Mean FEV1 ± SD was improved by 0.04 ± 0.02 in Theophylline therapy group while by 0.07 ± 0.01 in theTiotropium therapy treated group and a significant difference between the changes in th...
