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Local Drug Delivery to Treat Chronic Periodontitis
ISSN: 2617 - 9482
Publisher: author
Local Drug Delivery to Treat Chronic Periodontitis
Indexed in
Health Sciences
ARTICLE-FACTOR
1.3
Article Basics Score: 3
Article Transparency Score: 2
Article Operation Score: 2
Article Articles Score: 2
Article Accessibility Score: 3
SUBMIT PAPER ASK QUESTION
International Category Code (ICC):
ICC-0702
Publisher: Bahria University Medical And Dental College
International Journal Address (IAA):
IAA.ZONE/261797799482
eISSN
:
2617 - 9482
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Abstract
Periodontal disease is a chronic inflammatory disease of periodontium characterized by increased pocket depth, clinicalattachment loss, sulcular bleeding, and bone loss. Bacterial plaque bio-film stimulates host derived enzymes and cytokineslike TNF, IL-1 and matrix metalloproteases that lead to destruction of periodontium, collagenolytic activity, decreasedbone mineral density, intra-bony defects and ultimately bone loss. Chronic periodontitis is managed by conventional andsystemic approach, where conventional therapy comprises of scaling and root planning. Mechanical debridement of plaquealso requires an adjunct to eradicate the root cause of progressing disease. Hence, worldwide paradigm has shifted towardsnovel therapies; therefore, local delivery of drug is now preferred due to direct access to target sites with considerably lessadverse effects and a better approach to deal with chronic periodontitis. The nano-particle technology...
