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Protective Effects Of Tecomella Undulata Stem Bark Extract On IsoniazidInduced Hepatotoxicity: Based On Liver Enzymes ...
ISSN: 2617 - 9482
Publisher: author
Protective Effects Of Tecomella Undulata Stem Bark Extract On IsoniazidInduced Hepatotoxicity: Based On Liver Enzymes ...
Indexed in
Health Sciences
ARTICLE-FACTOR
1.3
Article Basics Score: 2
Article Transparency Score: 2
Article Operation Score: 3
Article Articles Score: 3
Article Accessibility Score: 2
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International Category Code (ICC):
ICC-0702
Publisher: Bahria University Medical And Dental College
International Journal Address (IAA):
IAA.ZONE/261797959482
eISSN
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2617 - 9482
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Abstract
Objective: To evaluate the hepatoprotective effects of Tecomellaundulata stem bark extract on isoniazid induced hepaticdamage based on liver enzymes and Liver function test in rat models.Study design and Setting: An experimental study conducted at Department of Pharmacology at Al-Tibri Medical Collegeand Hospital, Isra University Karachi Campus and Dow University of Health Sciences, Karachi.Methodology: Total twenty-four rats were studied. The albino rats that were male, healthy, and weighing 200-250gramswere included in this study. Rats were divided into four groups, each group having six rats and treated once daily orallyfor 30 days. Group A was control group and treated with normal animal diet and water; Group B was Isoniazid treatedgroup and induced by oral administration of Isoniazid (INH) 50mg/kg. Group C was treated with Isoniazid 50mg/kg andTecomellaundulata bark extract with low dose of 200mg/kg . Group D was treated with Iso...
