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The Triad Of PCOS, Infertility And Metformin
ISSN: 2617 - 9482
Publisher: author
The Triad Of PCOS, Infertility And Metformin
Indexed in
Health Sciences
ARTICLE-FACTOR
1.3
Article Basics Score: 2
Article Transparency Score: 3
Article Operation Score: 2
Article Articles Score: 2
Article Accessibility Score: 3
SUBMIT PAPER ASK QUESTION
International Category Code (ICC):
ICC-0702
Publisher: Bahria University Medical And Dental College
International Journal Address (IAA):
IAA.ZONE/261798869482
eISSN
:
2617 - 9482
VALID
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Abstract
Polycystic ovarian syndrome (PCOS) is now considered as a complicated disease of endocrine system. It is found in 5-10% of women of fertile age group. It was initially considered as a reproductive disorder in women. Studies in recent pasthave documented that PCOS is a metabolic syndrome and is influenced by genetic and environmental factors. It is alsotransferred genetically, an autosomal dominant trait with variable penetrance. Since role of insulin resistance has beenidentified as a main culprit in the development of PCOS therefore use of insulin sensitizers to treat PCOS seems logical.Insulin sensitizer such as metformin is a therapeutic option that targets not only insulin resistance present in this syndromebut several other aspects especially reproductive abnormalities such as infertility, which is a major problem of concern forwomen of reproductive age. This review attempts to cover the use of metformin in PCOS infertile women.K...
