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estorative Effect of L-Arginine on Gross Morphologyand Adrenal Weight in StreptozotocinInduced Diabetic Rats
ISSN: 2617 - 9482Publisher: author   
estorative Effect of L-Arginine on Gross Morphologyand Adrenal Weight in StreptozotocinInduced Diabetic Rats
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Health Sciences
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1.3
Article Basics Score: 3
Article Transparency Score: 3
Article Operation Score: 3
Article Articles Score: 3
Article Accessibility Score: 3
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International Category Code (ICC):
ICC-0702
Publisher: Bahria University Medical And Dental College
International Journal Address (IAA):
IAA.ZONE/261799719482
eISSN
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2617 - 9482
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Abstract
STZ) induced diabetic rats.Methodology: This experimental study was undertaken at the Department of Anatomy, Basic Medical Sciences Institute(BMSI), Jinnah Post graduate Medical Centre (JPMC), Karachi. Fifty healthy albino rats were equally divided into five groups.Group-A was taken as control. Group-B was treated with STZ. Group-C was given STZ with insulin. Group-D received STZwith L-arginine and Group-E was administered STZ along with both L-arginine and insulin. After the confirmation of diabetesby STZ, treatment was continued for a period of 6 weeks. The animals were sacrificed at the end of 6 weeks. At the start andend of the study period mean body weight of animals was calculated. Effect of L-arginine was observed on body weight ofanimals and weight of adrenal glands and compared with insulin.Results:The decrease in mean body weight of animals due to STZ was less significant when L-arginine and insulin wereadded to the therapy....