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Effect of Nigella Sativa on Biochemical Changes inDoxorubicin- induced Nephrotoxicity in Albino Rats
ISSN: 2617 - 9482
Publisher: author
Effect of Nigella Sativa on Biochemical Changes inDoxorubicin- induced Nephrotoxicity in Albino Rats
Indexed in
Health Sciences
ARTICLE-FACTOR
1.3
Article Basics Score: 2
Article Transparency Score: 3
Article Operation Score: 3
Article Articles Score: 3
Article Accessibility Score: 2
SUBMIT PAPER ASK QUESTION
International Category Code (ICC):
ICC-0702
Publisher: Bahria University Medical And Dental College
International Journal Address (IAA):
IAA.ZONE/261799749482
eISSN
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2617 - 9482
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Abstract
ABSTRACT:Objective: To evaluate the protective effects of Nigella Sativa on biochemical changes in the kidney of Albino rat treated withDoxorubicin.Methodology: This experimental study was undertaken in April 2015 for a duration of 05 weeks at BMSI, JPMC. Forty Albinorats were divided into four groups, ten animals in each group. Group-A was taken as control. Group-B was treated withDoxorubicin (DOX). Group-C was given doxorubicin and Nigella Sativa (NS), and Group-D was treated with Nigella Sativaonly. At the end of the study, the serum urea and creatinine levels were measured.Results: The mean values (mg/dl) of serum urea and creatinine levels in group-A and B were 23.40±3.07, 0.61±0.059, 85.50±7.93,and 1.06±0.071 respectively. There was highly significant increase in the mean values of serum urea and creatinine levels ingroup-B when compared with group-A. Further, the mean values (mg/dl) of serum urea and creatinine levels in group-...
