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Protective Effect of L-Arginine on Streptozotocin-InducedDiabetic Nephropathy in Albino Rat
ISSN: 2617 - 9482
Publisher: author
Protective Effect of L-Arginine on Streptozotocin-InducedDiabetic Nephropathy in Albino Rat
Indexed in
Health Sciences
ARTICLE-FACTOR
1.3
Article Basics Score: 3
Article Transparency Score: 3
Article Operation Score: 3
Article Articles Score: 2
Article Accessibility Score: 2
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International Category Code (ICC):
ICC-0702
Publisher: Bahria University Medical And Dental College
International Journal Address (IAA):
IAA.ZONE/261799989482
eISSN
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2617 - 9482
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ISSN Validator
Abstract
ABSTRACT:Objective: This study was designed to evaluate the protective role of L-arginine on body weight, and absolute and relativekidney weight of Streptozotocin (STZ)-treated albino rats.Methodology: This experimental study was conducted in the department of Anatomy, Basic Medical Sciences Institute (BMSI),Jinnah Postgraduate Medical Centre (JPMC), Karachi, from February to March, 2010. In this study, 30 male albino rats weredivided into 3 groups, containing 10 animals each. Group-A was treated as control. Group-B animals received STZ in a doseof 37 mg/kg intraperitoneally (I/P) only once at the start of experiment. Group-C received L-arginine orally in a dose of 0.3mg/100 gram (G)body weight/day a week before STZ treatment. Body weight of animals was calculated at start and end ofthe study period, along with absolute and relative kidney weight and serum glucose level.Results: There was a highly significant increase in serum glucose...
