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A Comparative Study of the Effects of Ethanolic Extract of Sesamum indicum Seeds and Mesterolone on Some Testicular Mo...
ISSN: 2582 - 6751
Publisher: author
A Comparative Study of the Effects of Ethanolic Extract of Sesamum indicum Seeds and Mesterolone on Some Testicular Mo...
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Medical Sciences
ARTICLE-FACTOR
1.3
Article Basics Score: 2
Article Transparency Score: 3
Article Operation Score: 2
Article Articles Score: 3
Article Accessibility Score: 2
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International Category Code (ICC):
ICC-1702
Publisher: Athenaeum Scientific Publishers
International Journal Address (IAA):
IAA.ZONE/2582117406751
eISSN
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2582 - 6751
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Abstract
Abstract Aim: The study aimed at comparing the effects of ethanolic extract of Sesamum indicum seeds with mesterolone on some testicular morphometry following ketoconazole induced damage in Wistar rats. . Methods: Thirty-six (36) adult male Wistar rats were divided into six (6) groups of six rats each. Groups 1,2,3,4,5 and 6 were administered 1 ml of normal saline, 100 mg /kg body weight (bwt) of Ketoconazole only, 500 mg/kg bwt of Ethanolic Extract of Sesamum indicum (EESI) seeds then 100 mg/kg bwt of Ketoconazole,100 mg/kg bwt of Ketoconazole then 250 mg /kg body weight of EESI seeds,100 mg/kg bwt of Ketoconazole then 500 mg/kg bwt of EESI, 100 mg/kg body weight of Ketoconazole, respectively. All administrations were carried out orally and once per day. The histological slides were prepared for morphometric analyses. Results: No observed significant differences in the morphometry of the groups administered EESI and Mesterolone. Howe...
