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Evaluation of Epileptogenic Focus by DWI in Temporal Lobe Epilepsy
ISSN: 2687 - 5365Publisher: author   
Evaluation of Epileptogenic Focus by DWI in Temporal Lobe Epilepsy
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Medical Sciences
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1.3
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International Category Code (ICC):
ICC-1702
Publisher: Necati Ozpinar
International Journal Address (IAA):
IAA.ZONE/2687120415365
eISSN
:
2687 - 5365
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Abstract
Temporal lobe epilepsy (TLE) is the most common focal epileptic syndrome in population. Mesial temporal sclerosis (MTS) is a frequent structural abnormality in medically intractable TLE. In this study, we aimed quantitative evaluation of epileptogenic focus using interictal diffusion-weighted magnetic resonance imaging (MRI) method in patients with temporal lobe epilepsy. A total of 72 TLE patients who underwent cranial MRI and 35 control cases were included in this study. 34 hippocampal sclerosis (HS) patients and 38 normal patients were evaluated. Patients were divided into two subgroups as MTS+ and MRI-negative TLE. The measurements of ADC were obtained from the hipocampus head, corpus, tail, amygdala, temporal lobe white matter and cortex bilaterally in the axial ADC map and compared between the groups. In the MTS group, predictive cutoff levels of hippocampal ADCs for identifying pathologic areas were established through receiver...