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Value of Gingival Crevicular Fluid Levels of Biomarkers IL-1 β, IL-22 and IL-34 for the Prediction of Severity of Peri...
ISSN: 2687 - 5365
Publisher: author
Value of Gingival Crevicular Fluid Levels of Biomarkers IL-1 β, IL-22 and IL-34 for the Prediction of Severity of Peri...
Indexed in
Medical Sciences
ARTICLE-FACTOR
1.3
Article Basics Score: 3
Article Transparency Score: 3
Article Operation Score: 2
Article Articles Score: 3
Article Accessibility Score: 2
SUBMIT PAPER ASK QUESTION
International Category Code (ICC):
ICC-1702
Publisher: Necati Ozpinar
International Journal Address (IAA):
IAA.ZONE/2687120435365
eISSN
:
2687 - 5365
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Abstract
Interleukins (IL) -1β, -22 and -34 play a crucial role in osteoclastogenesis and bone resorption through modulating inflammatory processes and osteoclastogenesis. To date, there is no study investigating both gingival crevicular fluid (GCF) ILs -22 and -34 levels before and after non-surgical periodontal treatment in patients with aggressive periodontitis (AgP) and chronic periodontitis (CP). We aimed to examine the relationship of GCF levels of biomarkers IL-1 β, IL-22 and IL-34 with the clinical evidence of periodontal tissue breakdown and alveoler bone resorption and to determine the value of these biomarkers for the prediction of severity of periodontal diseases and outcome of non-surgical periodontal treatment. Thirty-five AgP patients, 30 CP patients and 30 periodontally healthy volunteers (C) were included in this research. The AgP and CP patients underwent scaling and root planning interventions, performed with periodontal han...
