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Amoebicidal activity of Consolida orientalis (Gay.) Schröd. on Acanthamoeba castellanii cysts and trophozoites and it...
ISSN: 2687 - 5365
Publisher: author
Amoebicidal activity of Consolida orientalis (Gay.) Schröd. on Acanthamoeba castellanii cysts and trophozoites and it...
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Medical Sciences
ARTICLE-FACTOR
1.3
Article Basics Score: 2
Article Transparency Score: 2
Article Operation Score: 3
Article Articles Score: 2
Article Accessibility Score: 3
SUBMIT PAPER ASK QUESTION
International Category Code (ICC):
ICC-1702
Publisher: International Journal Of Academic Medicine And Pharmacy Ne..
International Journal Address (IAA):
IAA.ZONE/268743105365
eISSN
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2687 - 5365
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Abstract
In this study, it was aimed to investigate the effects of Consolida orientalis on Acanthamoeba castellanii (A. castellanii) cyst and trophozoites and cytotoxic potentials of plant extracts. Axenic cultures of A. castellanii trophozoites and cysts were prepared to test the amibicidal activity of Consolida orientalis. Consolida orientalis concentrations of 5 mg / 100 µL, 2.5 mg / 100 µL, 1.25 mg / 100 µL and 0.6 mg / 100 µL were prepared in 24-well plates and A. castellanii cysts and trophozoites were cultured in these mediums. Parasites were counted in cell counting device at 0, 1, 3, 6, 12, 24 and 48 hours after staining with trypan blue. In addition, the cytotoxicity of Consolida orientalis on the WI-38 human fibroblast cell line was tested with the XTT test. When A. castellanii, which was exposed to different concentrations of Consolida orientalis flower extracts, was examined, no live cyst and trophozoite were found at the conc...
