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Tweak Levels in Rheumatic Inflammatory Diseases
ISSN: 2687 - 5365Publisher: author   
Tweak Levels in Rheumatic Inflammatory Diseases
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Medical Sciences
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1.3
Article Basics Score: 3
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International Category Code (ICC):
ICC-1702
Publisher: International Journal Of Academic Medicine And Pharmacy Ne..
International Journal Address (IAA):
IAA.ZONE/268781985365
eISSN
:
2687 - 5365
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Abstract
The objective of this study is to investigate and compare serum levels of tumor necrosis factor-like weak inducer of apoptosis (TWEAK) in rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and Behçet's disease. Patients with a diagnosis of RA (n = 20), SLE (n = 20) and Behçet's disease (n = 20) and a healthy control group (n = 19) were included in our study. Disease activity indexes, erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) levels were recorded in the patient groups. Serum TWEAK levels were measured with available commercial enzyme linked immunosorbent assay kits. The serum TWEAK levels were significantly higher in all patient groups compared to the control group. However, no significant difference was found in paired comparisons among patient groups. When the patients with high disease activity scores were compared to patients with low disease activity scores in RA, SLE and Behçet’s disease su...