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RADIOGRAPHIC AND IMMUNO HISTOCHEMICAL DIAGNOSTIC STUDY OF STRONTIUM RANELATE AND METAL-SUBSTITUTED HYDROXYAPATITE BONE...
ISSN: 2320 - 5407
Publisher: author
RADIOGRAPHIC AND IMMUNO HISTOCHEMICAL DIAGNOSTIC STUDY OF STRONTIUM RANELATE AND METAL-SUBSTITUTED HYDROXYAPATITE BONE...
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Science General
ARTICLE-FACTOR
1.3
Article Basics Score: 2
Article Transparency Score: 2
Article Operation Score: 3
Article Articles Score: 2
Article Accessibility Score: 2
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International Category Code (ICC):
ICC-1402
Publisher: International Journal Of Advanced Research (ijar) Dr Morse
International Journal Address (IAA):
IAA.ZONE/232073595407
eISSN
:
2320 - 5407
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Abstract
Objective: The aim of the present study is to assess the radiographic and immunohistochemical effect of strontium ranelate (SR) and metal substituted hydroxyapatite (MSHA) on the treatment of chronic periodontitis among diabetic rats Materials and Methods: The study involved ten adult male and female rice rats (1-month-old) weighting (250- 300g). After a 24-hour fast, a single intraperitoneal dose of freshly prepared alloxan was injected to induce diabetes. A month after the injection of alloxan, the rats were randomly assigned to one of the two treatment modalities: SR with gengigel or MSHA with gengigel. Digital periapical radiography was taken at baseline, a month after the injection of alloxan to see resorbed alveolar bone and after 3months post-operative surgery for radiographic assessment. The diabetic rats were sacrificed using an overdose of anesthesia, and gingival tissue samples were collected. The specimens were processed f...
