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Future plans of Treating a Case of Acquired Pure Red Cell Aplasia Secondary to Autoimmune Causes Resistant to Combinat...
ISSN: 2583 - 2778Publisher: author   
Future plans of Treating a Case of Acquired Pure Red Cell Aplasia Secondary to Autoimmune Causes Resistant to Combinat...
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Technology and Engineering
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1.3
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International Category Code (ICC):
ICC-1802
Publisher: Genesis Scientific Publications
International Journal Address (IAA):
IAA.ZONE/2583413912778
eISSN
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2583 - 2778
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Abstract
Pure red cell aplasia (PRCA) is an orphan disease, and as such there are no rationally developed standard treatments. Most of the cases are idiopathic with a subset being antibody mediated. An overlap exists among idiopathic cases with those of T cell large granular lymphocytic leukemia, hypogamma globulinemia as well a slow grade lymphoma. Here we report a case of acquired Pure red cell aplasia (aPRCA), who did not attain Complete remission (CR) with calcineurin inhibitor (cyclosporine A) along with prednisone 50 mg od, being associated with 2 autoimmune disorders like systemic lupus erythemzatosus (SLE) with endometriomas and has now displayed partial remission (PR) with a combination of prednisolone 50mg with anabolic steroid danazol 200mg bd for 4 months along with metoclopramide 10mg od and is being continued on same therapy for minimum of 18 months for getting a CR as did another case of SLE as well as a case of anky losing spon...