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In Vitro Screening for Antioxidant and Anticholinesterase Effects of Uvaria littoralis Blume.: A Nootropic Phytotherap...
ISSN: 2292 - 2598
Publisher: author
In Vitro Screening for Antioxidant and Anticholinesterase Effects of Uvaria littoralis Blume.: A Nootropic Phytotherap...
Indexed in
Medical Sciences
ARTICLE-FACTOR
1.3
Article Basics Score: 2
Article Transparency Score: 2
Article Operation Score: 3
Article Articles Score: 3
Article Accessibility Score: 2
SUBMIT PAPER ASK QUESTION
International Category Code (ICC):
ICC-1702
Publisher: Lifescience Global Inc.
International Journal Address (IAA):
IAA.ZONE/2292109602598
eISSN
:
2292 - 2598
VALID
ISSN Validator
Abstract
Background: Oxidative stress is strongly linked in the development of numerous chronic and degenerative disorders. Medicinal plants with antioxidant and anticholinesterase activities exert a key role for the management of oxidative stress related disorders mainly Alzheimer's disease (AD). Therefore the purpose of this study was to assess antioxidant potentiality and anticholinesterase inhibitory activity of crude methanolic extract (CME), petroleum ether fraction (PEF), chloroform fraction (CLF), ethyl acetate fraction (EAF) and aqueous fraction (AQF) of Uvaria littoralis (U. littoralis) leaves. Methods: The antioxidant compounds namely total flavonoids contents (TFCs) and total proanthocyanidins contents (TPACCs) were determined for quantities constituent’s characterization. Antioxidant capacity of U. littoralis leaves were estimated by the iron reducing power (IRPA), 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging and nitri...
