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Public Article
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    Central Precocious Puberty as a Sign of Congenital Adrenal Hyperplasia: Case Presentations

     
     
         
    ISSN: 1929 - 4247

    Publisher: author   

Central Precocious Puberty as a Sign of Congenital Adrenal Hyperplasia: Case Presentations
Indexed in Health Sciences
ARTICLE-FACTOR
 1.3
Article Basics Score: 2
Article Transparency Score: 3
Article Operation Score: 2
Article Articles Score: 3
Article Accessibility Score: 3
Article Problems
Under Evaluation
article Flaws Reduces Credit

SUBMIT PAPER ASK QUESTION
International Category Code (ICC):
ICC-0702
Publisher: Lifescience Global Inc.
Authors: R.L. Markosyan, L.V. Navasardyan1,2
International Journal Address (IAA):
IAA.ZONE/192990634247
eISSN : 1929 - 4247 VALID ISSN Validator
Abstract Central precocious puberty results from the premature activation of the hypothalamic-pituitary-gonadal axis. Rarely congenital adrenal hyperplasia and/or its inappropriate treatment can be a peripheral cause of CPP. There are very few case reports of this etiology. Chronic mildly to moderately elevated adrenal androgens or intermittent hyperandrogenemia in congenital adrenal hyperplasia may trigger the precocious activation of the hypothalamic-pituitary axis, leading to CPP. In the current work, we describe 6 cases of late diagnosis of congenital adrenal hyperplasia associated with central precocious puberty. Central precocious puberty seems to be a complication of congenital adrenal hyperplasia, particularly in countries where a routine neonatal screening program for this condition is lacking. It is unclear whether these patients could avoid central precocious puberty development if the congenital adrenal hyperplasia was diagnosed in...
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